5 Days In Rome, The Perfect Rome Itinerary

With its ethereal beauty and rich history, Rome is a magical mecca of ancient architecture and carbs.

Over the centuries, Rome has accumulated layers of beauty, history, and romance, eagerly awaiting the arrival of those who come to admire it. I simply can’t resist the city and have visited many times.

If you’re planning a trip to the Eternal City, my 5 days in Rome itinerary gives you a detailed, step-by-step guide for exploring the city in the most efficient way.

Snapshot Of 5 Days In Rome Itinerary

Here’s what you’ll see with 5 days in Rome.

  • Day 1: Imperial Rome, Monti, Capitoline Hill
  • Day 2: Centro Historico, Borghese Gallery
  • Day 3: Vatican City, Trastevere
  • Day 4: Rome Hidden Gems
  • Day 5: Day Trip to Tivoli or Orvieto

You may be tempted to rush through Rome in fewer than 5 days. I have myself.

But Rome has so much to offer and discover — mind blowing art, charming neighborhoods, perfect wine bars. It’s better to slowly savor the wealth of art and cuisine that’s before you.

beautiful old buildings in Rome

You’ll need a plan of attack and pre-purchased tickets if you want to hit all of Rome’s key cultural sites and ramble among the rubble properly.

So channel your badass gladiator and read on for the full scoop on the best things to see, do, eat, and gasp at in Rome.

As with all of my suggested itineraries, I recommend that you use this 5 days in Rome itinerary as a guide. You can tailor it to suit your individual interests, needs, and pace of travel. 

the Colosseum
the Colosseum

5 Days In Rome Itinerary

Day 1 AM: Imperial Ruins

Begin your day by visiting the Imperial ruins tour, which includes the iconic Colosseum, Palatine Hill, and the Roman Forum.

I never tire of it. These sites can be visited with one trifecta ticket or ticket or on a guided tour and are Rome’s biggest draw. You can gaze in awe at the birthplace of Western civilization.

1. The Colosseum

The Colosseum, also known as the Flavian Amphitheatre, stands at a towering height of 600 feet and was officially inaugurated in 80 A.D. during an extravagant 10-day festival.

Over the centuries, it has become synonymous with spectacles involving gladiators, chariots, and the infamous “thumbs up or thumbs down” decree by the emperor. Within its walls, gladiators and wild animals engaged in deadly combat for the entertainment of the masses.

view of the underground Colosseum
view of the underground Colosseum

When visiting the Colosseum, make sure to explore the arena floor, where all the action unfolded, and take in the special boxes and podiums reserved for the emperor, vestal virgins, and senators.

Additionally, the top level of the Colosseum, which includes seating for the common people, was reopened in 2017. This vantage point offers breathtaking panoramic views and might just be the highlight of your visit.

I also recommend booking a guided tour that takes you to the hypogeum or the Colosseum Underground. You won’t see this on a standard tour.

You’ll be able to inspect animal cages, gladiator corridors, back stairs used by the slaves, trap doors, and the launching point for mock naval battles.

Tip: If you’re DIY-ing the Colosseum, you need to reserve your entry time online well in advance. This is true even if you have a skip-the-line Roma Pass.

Domitian's Palace on Palantine Hill
Domitian’s Palace on Palantine Hill

2. Palatine Hill

Palatine Hill has enough raw beauty and buried mystery to restore the rosy tint of Rome to any jaundiced eye.

It’s a lovely setting, lush and green, with plenty of benches and a viewing terrace.

This is where the rich and famous of Imperial Rome lived. None of the structures are terribly intact. And you might find it hard to identify the ruins.

The most impressive one is the ruins of Domitian’s Palace, which included private and public areas.

But there are three other noteworthy stops.

Domus Tiberiana is an ancient Roman palace, notable for its connection to the early emperors and its impressive architectural remains. It recently opened to the public for the first time in September 2023.

The House of Augustus is the former residence of Emperor Augustus, offering visitors a glimpse into the life of one of Rome’s most influential figures. Its red Pompeiian style frescos are some of the finest in Italy.

My last time in Rome, I took a this guided tour with a PhD and loved the sound and light show. It takes place three times a day.

Finally, the Palatine Museum, located near the Domus Tiberiana and House of Augustus, houses an extensive collection of archaeological artifacts and art from the Roman Republic through the Roman Empire.

Temple and House of the Vestal Virgins
House of the Vestal Virgins

3. The Roman Forum

After Palatine Hill, you move on to the Roman Forum, the very core of antiquity. This was where Romans shouted “Caesar has been murdered” and crowded to hear Mark Anthony’s eulogy.

I advise having a guided tour here. There’s not much signage. It will be difficult to divine what you’re looking at without a guide to decipher the lovely rubble and ruins.

The forum is a rectangular valley running from Arch of Titus to the Capitoline Hill. The main road is the Via Sacre.

The forum was the beating heart of Rome, the seat of power, and its central showpiece. It was a grandiose public district consisting of white temples, grand basilicas, and vibrant public spaces.

Stroll by the Arch of Titus, the Basilica of Constantine, the Temple and House of the Vestal Virgins (home to the sacred flame of Rome), and the 3 columns of the Temple of Castor and Pollux.

You’ll also find a small temple to Julius Caesar. Inside, is a mound of dirt covered with coins and flowers that marks his grave.

If you buy the SUPER ticket on Viator, you can also visit the Church of Santa Maria Antiqua.

It’s renowned for its early Christian frescos that are nicknamed the “Sistine Chapel of the Middle Ages.” Two rooms feature a sound and light show that fills in the blanksand shows you what the frescos looked like in their day.

the picturesque Rione Monti in Rome, with the Basilica of Santa Maria Maggiore in the background

Day 1 PM: Monti and Capitoline Hill

After you’ve finished exploring the ruins, take a short 5-10 minute stroll to Rome’s neighboring Monti district.

Monti is the city’s trendiest area, teeming with one-of-a-kind shops and trendy dining spots. You can enjoy a delicious lunch at one of the restaurants along Via Panisperna or Via Urbana.

One absolute must-see attraction in Monti is the Santa Maria Maggiore Church, a personal favorite of mine even compared to St. Peter’s Basilica.

This historic church boasts an older pedigree, dating back to the 5th century A.D., and it mesmerizes visitors with its stunning mosaics adorning the triumphal arch and nave.

For more mosaics, including the stunning Chapel of San Zeno, you can pop into Santa Prassede, which is just around the corner.

Tip: Monti is also a great place to take a guided food tour or a guided wine tasting tour.

Basilica of Santa Maria Maggiore in Rome's Monti neighborhood
Basilica of Santa Maria Maggiore in Rome’s Monti neighborhood

When you’re done in Monti, head over to the the Vittorio Emanuel II monument on Capitoline Hill, also known as the “typewriter” or “wedding cake” building. For views, hike up to the second floor.

For even better views, book a ticket for the elevator around the back up to the viewing terrace. It’s a fairly pricey, but I thought it was worth every penny.

I personally thought this view was better than the view from St. Peter’s Basilica because it was closer to the ancient Roman sites.

When you’re done swooning over views, head back down the stairs. Take a left at the bottom of the stairs and then another left.

staircase leading up to the Michelangelo-designed Piazza del Campidoglio
staircase leading up to the Piazza del Campidoglio

A few 100 feet later, you’ll see Michelangelo’s stairway, rising to the Piazza del Campidoglio at the top of Capitoline Hill.

Take the stairs up. At the top is the wonderful Capitoline Museums, housed in two buildings connected by an underground passage. In high season, you’ll want to pre-book a skip the line ticket.

Inside, are some of Rome’s greatest treasures — the Equestrian Statue of Marcus Aurelius, the original She-Wolf of Rome that suckled Romulus and Remus, and other ancient statues.

After exiting the museum, head down the alleyway on the right side of the square under an arched building. That will take you to a viewpoint over the Roman Forum. This is the best view you’ll have of the forum.

Largo di Torre Argentino, the site of Caesar's assassination
Largo di Torre Argentino, the site of Caesar’s assassination

You could also make a quick detour to the Church of Santa Maria d’Araceli. It’s an ancient brick church. The church is mostly known for its beautiful frescos by Pinturicchio, an early Renaissance artist. 

When hunger calls after this hectic day, head to the atmospheric Jewish Ghetto neighborhood. It’s just a stone’s throw away, on the banks of the Tiber River.

On your way, visit Largo di Torre Argentina. These are the ruins of the Theater of Pompey, the very spot where Caesar was assassinated. They opened in 2021. But it was not until June 2023 that walkways were installed so you can see the ruins up close.

I just wandered around the evocative Jewish Ghetto. But you also book a guided walking tour of this historic neighborhood, if you want something more structured or are interested in the history.

flower stalls at Campo dei Fiori
flower stalls at Campo dei Fiori

Day 2 AM: Central Rome

Begin day 2 of your 5 days in Rome with a classic walk through Rome’s Centro Storico. Start at Campo de’ Fiori and end at the Spanish Steps, visiting the Trevi Fountain, Piazza Navona, and the Pantheon along the way.

You can follow my walk (linked above) on your own. Alternatively, you can also book a private walking tour of this beautiful part of Rome.

1. Campo de’ Fiori

Campo de’ Fiori is Rome’s colorful market square.

In the center is a statue of Giordano Bruno, a 16th century friar and philosopher who was imprisoned in Castle Sant’Angelo and burned at the stake for his scientific theories.

Here, you’ll find fresh produce and can pick up some souvenirs like olive oil, pasta, or limoncello. There are also a cluster of contemporary art galleries near the Campo.

Borromini's Church of Sant'Agnese in Piazza Navona
Borromini’s Church of Sant’Agnese in Piazza Navona

2. Piazza Navona

Your next stop is the Piazza Navona, sometimes called the Square of Fountains. Piazza Navona is the very symbol of Rome.

This famous square is a long rectangle, dotted with beautiful fountains designed by Gianlorenzo Bernini and outdoor cafes. It dates back to the time of Domitian, who used it as a racetrack. Today’s buildings date from the 16th century.

Be sure to pop into the beautiful Church of Sant’Agnese designed by Borromini. Borromini was an Italian architect who helped launch Roman Baroque architecture.

Everyone goes to Piazza Navona and admires the striking concave facade. Most people don’t step inside the church. Do it, it’s free!

Pink and white marble covers the walls. The bright and simple interior is filled with Baroque statues. Beautiful frescos decorate the dome.

Tip: If you love ancient sculpture the Palazzo Altemps is a lovely museum at the northern end of the piazza.

Caravaggio paintings in the Contarelli Chapel
Caravaggio paintings in the Contarelli Chapel

3. Church of Sant’Agnese and St. Louis of the French

Just one block from Piazza Navona is the Church of St. Louis of the French. You can enter for free.

The highlight is the Contarelli Chapel, which holds three stunning Caravaggio paintings. If you’re an art lover, you can’t miss this spot!

the Pantheon, Rome's most ancient temple
the Pantheon, Rome’s most ancient temple

4. Pantheon

Then you’re off to Rome’s most famous temple, the 2,000 year old Pantheon, set in a lively piazza. This is my favorite building in Rome.

The entrance boasts massive 40 foot single piece granite columns. The pediment proclaims that Marcus Agrippa, Augustus’ right hand man, built the Pantheon. In fact, it was built by Hadrian.

Inside is a magnificent dome with a giant oculus (or eye in the sky) that inspired the domes of St. Peter’s Basilica and the Duomo in Florence.

If it’s raining, water falls through the oculus and drains out the floor.

Pantheon interior
Pantheon interior

One of the greatest painters of the Renaissance, Raphael, is buried in the Pantheon. His tomb sports a sculpture by Lorenzo Lotti that Raphael himself commissioned.

>>> Click here to pre-book a ticket and avoid lines

Just one block away from the Pantheon, you should make a quick stop at the Basilica of Santa Maria Sopra Minerva. The plain facade belies the treasures inside.

The Minerva is a mini-museum, with frescos and sculptures by some of the greatest artists of the Renaissance and Baroque.

Tip: You can also book a guided tour of both the Pantheon and Sopra Minerva.

Column of Marcus Aurelius in Piazza Colonna
Column of Marcus Aurelius in Piazza Colonna

5. Piazza Colonna

Then, stroll to the Piazza Colonna. This square features the massive Column of Marcus Aurelius carved from Carrara marble.

Reliefs wrap around the column telling stories of Marcus Aurelius’ war exploits.

The exploits were exaggerated because Rome had already begun losing skirmishes with the barbarians.

READ: Guide to the Gorgeous Palazzo Colonna

6. Mausoleum of Augustus or Ara Pacis

Fans of the first Roman emperor will want to visit the Mausoleum of Augustus and/or the Ara Pacis Museum. They’re right next door to each other.

Dating from 28 B.C., the mausoleum is Augustus’ monumental family tomb, built in his 30s, shortly after he became emperor. Talk about your own sense of destiny!

Everyone in the Julio-Claudian dynasty is buried there — Augustus, Livia, Octavia, Agrippa, Germanicus, Tiberius, Caligula, etc. Though Augustus did ban family members he considered disloyal, like his own daughter Julia.

The Ara Pacis, or Altar of Peace, is one of Ancient Rome’s most significant monuments. Built in the 1st century BC, this 2,000 year old altar symbolizes the peace and prosperity of Emperor Augustus’s reign.

It’s covered in gorgeous relief sculptures. They show Augustus’ family, processional scenes, mythological images, and a cornucopia of vegetal and floral motifs.

>>> Click here to pre-book a skip the line ticket

the Trevi fountain with the figure "Ocean" in the center
Trevi Fountain

7. Trevi Fountain

Further on is the famous Trevi Fountain, an imposing Baroque monument designed by architect Nicola Salvi. The fountain was immortalized in Fellin’s La Dolce Vita.

The fountain is 85 feet high and 65 feet wide, making it Rome’s largest fountain. In the center is the figure “Ocean.” Water pours from 24 spouts.

If you’re superstitious, toss a coin over your shoulder to ensure your return to Rome. Over 3,000 euros are collected from the fountain daily and donated to charity.

If you didn’t lunch earlier, you have options. There’s a cute little hole in the wall restaurant nearby, Ristorante Sora Lucia, which serves up delicious gnocchi for locals.

Piccolo Buco is also a tiny and delicious pizzeria only one minute from the Trevi Fountain. And La Prosciutteria serves up killer porchetta sandwiches.

the Sinking Boat Fountain in the Piazza di Spagna in front of the Spanish Steps
the Sinking Boat Fountain in the Piazza di Spagna

8. Spanish Steps

After lunch, head down Via Sistina to the Spanish Steps. It’ one of Rome’s iconic sites.

This grand staircase of 135 steps connects the Piazza di Spagna at its base to the Trinità dei Monti Church at the top.

Visitors and locals alike gather here to relax, people-watch, and take in the picturesque views of Rome, making it a popular spot for both tourists and Romans.

At the foot of the steps is another famous Bernini fountain, the Sinking Boat Fountain.

Borghese Gallery
Borghese Gallery

Day 2 PM: Borghese Gallery

After lunch, take in one of my favorite art museums in the world — the Borghese Gallery. You may think I’m exaggerating, but I’m not. Incredible masterpieces are set in a stunning villa filled with frescos and marble.

The villa was commissioned in 1613 by Cardinal Scipione Borghese to house his impressive collection of Roman, Renaissance, and Baroque art.

The cardinal was a fan of Bernini and helped him rise to fame. An ardent and obsessed collector, he acquired art work by unscrupulous means, once stealing a painting from a convent altar in the dead of night.

READ: Bernini Guide to Rome

You’ve got to pre-book a ticket well in advance to visit the Borghese Gallery. Only a set number of people are allowed in every two hours. You can’t purchase a ticket at the museum itself.

Your visit will start in the Pinacoteca, or painting gallery, on the upper floor. But budget most of your time for the first floor.

Arrive early and only carry a very small purse or bag. Everything else must be checked, no exceptions. There are information placards in each room. But an audio guide will educate you on the must see highlights more easily.

In the Pinacoteca, you’ll find some Bernini self portraits and smaller sculptures. You’ll also find two of Raphael’s most famous works — The Deposition and Young Woman with a Unicorn. Both paintings are currently undergoing diagnostics for conservation work.

The bottom floor is overflowing with perfectly arranged masterpieces. The sculptures by Bernini, who almost single handedly invented the Barqoue style, steal the show. The most beautiful ones are The Rape of Persephone, Apollo and Daphne, and David.

There’s also a stunning work by Antonio Canova, Pauline Borghese as Venus. And a room filled with Caravaggio’s art, including his famous David with the Head of Goliath.

Click here for to book a guided tour of this magnificent museum.

Piazza del Popolo
Piazza del Popolo

Piazza Popolo

When you’re done admiring the exquisite art, I recommend heading over to the west side of the Borghese Gardens, towards the Piazza del Popolo. The cobbled Renaissance square is home to Rome’s north gate and its largest obelisk.

Pop into the Basilica of Santa Maria del Popolo to see two beautiful Caravaggio paintings for free. Climb the stairs to the Pincio Terrace (directly above the piazza at the end of Via del Corso).

The view of the rooftops of Rome is quite beautiful, particularly at sunset.

There are some good restaurants near the Borghese Gallery, if you want to stay in the area for dinner. For gourmet food, try Oliver Glowig (Michelin-starred) or Sapori del Lord Byron. For a cozy informal setting, try Girarrosto Toscano.

Alternatively, you can take a food tour in Rome at night and find out what and where the locals eat. There are several options for all interests (I’ve done them all and feasted!’

view of St. Angel's Bridge and St. Peter's Basilica
view of Sant’Angelo Bridge and St. Peter’s Basilica

Day 3 AM: Vatican City

Start off day 3 of your 5 days in Rome with a bang by visiting Vatican City, the spiritual and administrative center of the Roman Catholic Church.

Unless you arrive on a weekend. You don’t want to go on a weekend, ever. It’s too crowded. So if your time in Rome falls on a Saturday or Sunday, flip flop the days of my sample itinerary around and push the Vatican to a weekday.

The Vatican holds one of the world’s greatest art collections. It’s a treasure trove of cultural and religious artifacts.

Some of the most famous art works on the planet are there. If you’re an art or history lover, the Vatican is an absolute must see site in Rome.

You absolutely must pre-book skip the line tickets for the Vatican. Or else you’ll be stuck in line for hours unless it’s the dead of winter. You may also want to book a guided tour and there are many options to choose from.

Raphael, School of Athens, 1509-11
Raphael, School of Athens, 1509-11, in the Raphael Rooms

Much of the work was collected by Pope Julius II, who left a staggering legacy. Julius rebuilt St. Peters Basilica.

He commissioned Michelangelo’s Sistine Chapel and the Vatican’s Raphael Rooms. In 1506, he founded the Vatican Museums.

The real highlight of the Vatican is the Sistine Chapel, adorned with Michelangelo frescos. Michelangelo spent 4 years toiling away on the 9 ceiling panels.

They depict scenes from Genesis and seem to open up the chapel to heaven. And he did it standing up, not laying down as legend holds.

In 1533, Pope Julius II summoned him back to Rome to paint The Last Judgment on the altar wall. This fresco is more monumental in style than Michelangelo’s ceiling frescos.

Michelangelo's Creation of Adam on the ceiling of the Sistine Chapel
Michelangelo’s Creation of Adam on the ceiling of the Sistine Chapel
detail from Michelangelo's The Last Judgment, on the altar wall of the Sistine Chapel
detail from Michelangelo’s The Last Judgment

In the middle, Christ is excessively youthful and floats on clouds. He’s depicted more like Apollo than the suffering bearded savior one expects.

When you’re done admiring the Vatican treasures, head to St. Peter’s Basilica. It’s the most famous church in Christendom.

Designed by Bramante, Raphael, and Michelangelo, it’s a true Renaissance masterpiece. The dome of St. Peters, designed by Michelangelo, is the tallest in the world.

The basilica is the burial place of St. Peter and past popes, has Bernini’s famous Baldachine altar, a plethora of Bernini sculptures, and Michelangelo’s tragically beautiful Pieta.

St. Peter's Square as seen from the dome of St. Peter's Basilica
St. Peter’s Square as seen from the dome of St. Peter’s Basilica

St. Peter’s is free to enter. But you may have a long security line. If you’re on your own, pick up an audio guide inside. It will take you on an hour long tour.

For just € 6, you can climb up a narrow flight of stairs to inspect the dome at close range. There’s also an elevator for € 8.

From there, you’ll have a bird’s eye view of the nave below.

Continue higher to stand on the outside of the dome. This is where you have the iconic view of St. Peter’s Square and a panoramic view of Rome.

Castle Sant'Angelo and the Bridge of Angels
Castle Sant’Angelo and the Bridge of Angels

You can take a guided tour of St. Peters or a tour that includes the underground grottos.

When you’re done Vatican-ing, head to the nearby Castle Sant’Angelo.

The castle is a cylindrical beauty at the end of the Sant’Angelo Bridge. It was once Hadrian’s Masoleum. It then served as a fortress, castle, papal residence, and (now) museum.

The castle is the perfect reflection of Rome’s history. Though Castle Sant’ Angelo owes its name to a medieval legend, its history dates back to ancient Rome. Visiting the Castle Sant’Angelo is a walk through the entire history of Rome in one go.

Click here to pre-book a ticket.

enjoying Vatican City on a blustery day in Rome
enjoying Vatican City on a blustery day in Rome

It’s worth going inside if you’re a real history buff. The Terrace of the Angel on top serves up stunning views of St. Peters and the surrounding area.

From here, unless you want to burn off some pasta, I recommend taking a taxi to Rome’s atmospheric Trastevere neighborhood.

Day 3 PM: Trastevere

On day 3 of your 5 days in Rome itinerary, head to Trastevere. This beautiful and charming Rome neighborhood is a village within a city, with the laidback vibes of small town Italy.

Trastevere is worth lingering in. Its lovely cobbled and cafe-lined streets are vastly quieter than the cacophony of central Rome.

Raphael frescos in the Loggia of Psyche in the Villa Farnesina
Raphael frescos in the Loggia of Psyche in the Villa Farnesina

You may want to book a guided walking tour or even take a fun Segway tour to get oriented.

If you haven’t yet had lunch, grab a delicious panini at La Proscuitteria (there’s a branch in Trastevere as well).

After a look around Trastevere, head into Villa Farnesina. It’s an underrated small museum in a beautiful setting that’s a quiet oasis of in situ art and architecture. 

The villa is only open weekdays until 2:00 pm. If you can get there at 1:00 pm, you’ll have an hour, which is all you need.

12th century mosaics showing Christ and his mother flanked by saints in the Santa Maria basilica in Trastevere
12th century mosaics in the Santa Maria Basilica in Trastevere

This sumptuously decorated villa was built in the early 1500s for one of Europe’s richest Renaissance men, Agostino Chigi. The villa has some magnificent mythological frescos by Renaissance painters Raphael, Peruzzi, and Sebastian del Piombo.

Then stroll to the lively Piazza di Santa Maria, which is the heart of Trastevere. Head into the Sant Maria Basilica, the oldest church dedicated to Mary in Rome.

The church itself dates from the 3rd century. But it’s outfitted with a 12th century Romanesque bell tower. Inside, in the apse, you can admire the beautiful 12th century mosaics.

Spend some time wandering the quaint alleys of Trastevere, admiring the golden and coral homes. Then, visit the Church of Santa Cecelia.

The exterior is a mishmash of architectural styles. But the interior is a luminous gold and cream combination.

Square Santa Maria in Trastevere
Square Santa Maria in Trastevere

It’s time for happy hour. Settle in for some wine at Enoteca Ferrara, which has a huge wine list. You can eat here too. I had a divine puttanesca.

If you want to move on in Trastevere, try Ombre Rosse.

Another restaurant I enjoyed is La Sora Lella on Isola Tiberna. It’s one of Rome’s oldest restaurants, serving up classic rustic food in a casual setting. You’ve got to make reservations for both places.

Today, take in some of Rome’s hidden gems.

San Clemente

In the morning start your day with a visit to the Basilica of San Clemente. It’s one of the most fascinating churches in the city.

San Clemente is microcosm of the architectural stratification that is a prime characteristic of Rome.

You enter a 12th century church, descend to a 4th century church below, and further down to 1st century spaces including a Mithraic temple. Along the way, you’ll see some beautiful mosaics and frescos.

Because this is such a historic site, you might consider booking a guided tour. There is signage, but you’ll get more out of the experience with a guide.

You can book a 1 hour small group tour or a a 2.5 hour private tour.

the Golden Vault of Domus Aurea
the Golden Vault of Domus Aurea

Domus Aurea

The ruins of Nero’s Golden House, Domus Aurea, are now open after years of excavation. Located on the Oppian Hill, you can only visit on Friday throughSunday with a hard hat. But Domus Aurea is worth the effort; it’s an exciting archaeological site.

Nero’s Golden House was once the grandest building on earth. Built by Emperor Nero between 64-68 AD, the sprawling property covered up to 300 acres.

The facade and walls were adorned with frescos, gold leaf, glass mosaics, pearls, and marble. In natural light, it had a golden hue.

But little of this wealth survived Nero’s rule. As Nero’s extravagance and tyranny spun out of control, rivals condemned both his reign and his emblematic palace.

For a decade after his death, the palace was looted, destroyed, and filled in with brick. But the vivid frescos by the artist Famulus couldn’t be pried off.

the Octagonal Room in Domus Aurea
the Octagonal Room in Domus Aurea

At the end of the 15th century, the Domus Aurea was discovered by accident when a young man fell into a crevice. To his surprise, he found himself surrounded by paintings.

At first, the palace ruins were thought to be caves or grottos. Artists like Michelangelo and Raphael flocked to see the ancient frescos.

In the 18th century, proper excavation of the Golden House began. The crown jewel is the Octagonal Room, which represented a revolution in architectural style and technique.

Since the site is only open on certain days, I advise booking a guided tour, with a virtual reality experience, well in advance.

When you’re done at Domus Aurea, head over to the nearby St. Peter in Chains, San Pietro in Vincoli. There, you can inspect one of Michelangelo’s most riveting sculptures, the statue of Moses on the tomb of Pope Julius II.

Michelangelo's Moses sculpture in the Church of St. Peter in Chains
Michelangelo’s Moses in the Church of St. Peter in Chains

Doria Pamphilj

One of my favorite secret gem museums is the Palazzo Doria Pamphilj (pronounced Pom-fee-lee). It’s simply a joy to visit, a heady blend of in situ art and magnificent 17th century architecture.

The art collection was meticulously assembled and is still owned by a powerful Italian family, the Doria Pamphilj. The museum boasts over 650 works spanning the 15th to the 18th century.

The collection includes pieces by Velazquez, Raphael, Bernini, Caravaggio, Titian, Carracci, and Bruegel. And it has a spectacular Hall of Mirrors. The palazzo also has one of Rome’s most beautiful gardens.

>>> Click here to pre-book a ticket

For dinner, make a reservation at one of the most authentic and unconventional restaurants and wine bars in centro historic, Roscioli.

It’s a small place, but with excellent food. After a full day on the streets of Rome, you’re owed a carbonara.

the conopus of Hadrian's Villa in Tivoli
the conopus of Hadrian’s Villa in Tivoli

Day Trip to Tivoli or Orvieto

I think the best and easiest day trips from Rome, via high speed train or tour, are Tivoli and Orvieto.

1. Tivoli: UNESCO Sites

While the town of Tivoli isn’t one of Italy’s most picturesque villages, Tivoli home to two magnificent UNESCO World Heritage Sites: the sprawling Hadrian’s Villa and the comely 16th century Villa d’Este, a Renaissance retreat.

You might want to book a tour, just to make it easier to visit both sites and get the historical backdrop.

READ: Best Day Trips From Rome

me at the Canopus of Hadrian's Villa

If you’re fond of ancient history or are ruin luster like me, you’ll be fascinated and thrilled by the evocative ruins of Hadrian’s Villa.

If you have ruin fatigue, Villa d’Este is a playground of whimsy, topped with a frescoed villa. The gardens are to die for — filled with sparkling fountains, moss draped grottos, and ponds filled with water lilies.

If you opt for Tivoli, you’ll get back early enough to take an evening stroll through Rome’s centro historic.

If you want to really splash out on your final dinner, try La Pergola, with three Michelin stars, at the Rome Cavalieri Hotel.

The hotel itself also has a superb art collection (you can schedule a tour with an art historian). If you want something more casual as you stroll, La Sagrestia is right near the Pantheon.

the magnificent Fountain of the Organ at Villa d'Este
the magnificent Fountain of the Organ at Villa d’Este

2. Orvieto: Cathedral Town in Umbria

A car free haven, Orvieto is a striking hill town. There are three reasons to day trip to the capital of Umbria — its beautiful cathedral with one of Italy’s most exciting facades, chianti, and ceramics.

Orvieto’s piece de resistance is its UNESCO-listed Orvieto Cathedral. It’s one of the most beautiful and ancient churches in Italy.

It’s a riveting ensemble of spires, spikes, golden mosaics, statuary, stained glass, and black and white striped marble. And that’s just the facade.

Inside, the Chapel of San Brizio is one fo the most beautiful chapels in Italy. It has a great Renaissance fresco cycles by Luca Signorelli.

cityscape of Orvieto
cityscape of Orvieto
Orvieto Cathedral
Orvieto Cathedral

Michelangelo came to inspect the chapel before beginning his own master work, the Sistine Chapel in the Vatican. The frescos depict the usual religious themes — temptation, damnation, and salvation.

If you opted for Orvieto, have apertivo and dinner there.

For inventive cuisine, try I Sette Consoli. If you want to eat in the remains of an Etruscan tomb, reserve at Al Pozzo Etrusco.

For some more detailed guidance on what to do, here’s my one day in Orvieto itinerary. You may want to book a guided day trip tour to Orvieto from Rome.

This tour includes both Orvieto and Assisi, another stunning town in Umbria that’s the home of St. Francis. You can also take an 8 hour guided tour to Orvieto and Civita di Bagnoregio, a tiny architectural stage set suspended in midair on a hilltop.

Great Hall of Palazzo Colonna
Great Hall of Palazzo Colonna

Must Know Tips For Rome

1. How To Get To Rome

You’ll likely fly in to Fiumicino Airport.

While I had decent luck with taxis in central Rome, one place you won’t fare well is Fiumicino Airport. The cabs aren’t well regulated and known to rip off tourists.

You may also encounter exceedingly long lines, especially on the weekends. Given this, I strongly advise booking a private transfer online, so you can skip the line.

You can also take the train. The Leonardo Express leaves every 15 minutes from the Felice Santini train station near the airport. 

It drops you off in Rome’s Termini Station, which is in northeast Rome. Click here to book a round trip ticket.

Tip: Right across the street from Termini is one of Rome’s best museums, the Palazzo Massimo. It’s a bastion of ancient sculpture and frescos.

Palazzo Barberini, an underrated museum in Rome
Palazzo Barberini, an underrated museum in Rome

2. How To Get Around Rome

Rome is a fairly walkable city. So bring really comfortable shoes, especially for the uneven cobblestones. I easily clocked 10 miles a day.

I’m not really a fan of Rome’s metro. It’s only 2 lines, very crowded, and known for pickpockets. The bus system was too confusing for my taste.

I thought it was easier and fastest to use taxis, if you’re going a fair distance (like from the Vatican to Trastevere). Look for them at taxi stands near major attractions.

It’s not very easy to flag them down on the street. Most will pretend they don’t take credit cards, so be sure to have cash. You can also use Uber.

Statue and Column of Emperor Trajan in via dei Fori Imperiali, Rome Italy
Statue and Column of Emperor Trajan in via dei Fori Imperiali

Definitely don’t have a car in Rome. The drivers are very aggressive and many streets are teeny tiny.

If you’re venturing outside Rome on an Italy road trip, pick up the car on your way out of Rome.

There are plenty of other fun ways to explore Rome, for every interest. You might consider booking one of these tours:

Gelateria del Teatro -- a great place for gelato and cannoli
Gelateria del Teatro — a great place for gelato and cannoli

3. When To Visit Rome

Try to visit Rome in the off season. Rome is one of the world’s most popular and busiest cities. It can be a chaotic, crowded, sweaty mess in the summer.

Fall and spring are lovely. Even in winter, you’ll have sunny days and mild temperatures.

If you must visit in high season, it’s essential to invest in skip the line tickets. Otherwise, the bulk of your day will be standing in lines and you won’t see nearly as much.

4. Rome City Passes

If you’re in Rome for 5 days, consider purchasing the Roma Pass. For just 38 euros, You’ll have full access to public transportation, admission to two museums, and discounts on performance and exhibition tickets.

Alternatively, try the more comprehensive Omnia Rome and Vatican Card. It consists of the Roma Pass and an Omnia Card.

bridge linking Trastevere and Isola Tibernia
bridge linking Trastevere and Isola Tibernia

Most importantly, it gives you skip the line access at the Vatican Museums, St. Peter’s Basilica, and the Colosseum.

5. Where To Stay In Rome

If you’re a first timer in Rome, you may want to stay in the historic center around the Pantheon or Piazza Navona. Some good options are the Liberty Boutique Hotel, the Hotel MaalatDeco Roma, or Hotel Hassler Roma.

If you want to stay near the Imperial ruins, Palazzo Manfredi and the Inn at The Roman Forum are good choices.

If you want to stay in the quieter Monti area, which makes a great base, the Palazzo Manfredi (Colosseum views), Villa Spalletti Trivelli (Roman townhouse), and Roma Luxus (former 18th century palace) are fantastic choices.

view of St. Peter's Square
view of St. Peter’s Square

One of my personal favorites is the Rome Cavalieri, which has its own art collection. You will also love the J.K. Place Roma, a simply gorgeous boutique hotel.

6. Departing Rome

Are you ending your trip in Rome? If so, you may want to drop off your car and stay at one of the airport hotels to fly out the next day.

The Hilton Rome Airport is the best place to stay. It’s just a few blocks away and you can easily roll your bags there.

Via dei Coronari in the historic center of Rome
Via dei Coronari in the historic center of Rome

If you’re staying at another airport hotel, you will need to take a taxi. Be sure to get in the line for local taxis, which is different than the regular taxi line. It’s across the street and up the stairs.

I hope you’ve enjoyed my 5 days in Rome itinerary. You may enjoy these other travel guides and resources for Italy:

If you’d like to spend 5 perfect days in Rome, pin it for later.

Pinterest pin for five days in Rome itinerary

6 thoughts on “5 Days In Rome, The Perfect Rome Itinerary”

  1. Hi Leslie, I love your blog and 5 day itinerary for Rome. My interests seam to be similar to yours and I will be using majority of your itinerary on my trip to Rome. However, I was wondering why you didn’t combine House of Augustus and Livia with the first day itinerary when you visited Colosseum, Roman Forum and Palatine? Would it make sense to purchase a full experience ticket and see all in one day?

    • Sure you could book the Full Experience ticket, which is a new ticket, and do it all in one day. But the ticket does give you 2 days to visit the sites. Thank you and I hope you have a great trip to Rome.

  2. Hi Leslie! Just want to say how much I like your site. I’m heading to Europe to visit a friend in September. I’m considering adding on a few days in Rome, but wondering if you think things will still be chaotic with tourists in mid-September. I’m hoping to avoid the summer rush to Europe’s biggest cities.


    • Thanks Jenn. It will still be crowded in September. But with everyone back in school and summer over, it will be bearable. Just purchase tickets in advance!

  3. Hi Leslie,
    Happened to come across your blog and WOW !! I am going to have to book another 4 days in Rome just to see it through your eyes. Loved all the information advice tips and WOW ..
    We have already booked a few things in so far for our two days that we have prior to getting on a cruise ship.
    So we would have seen the Colosseum Tour underground, arena floor, Roman Forum & Palatine Hill.. We have booked a tour for the Jewish Ghetto & Trastevere plus a Night Ghost walking tour.. we can fill it in with some of your ideas. Then when we get back into Rome after the cruise we can add a few extra days to finish off what you started

    We also want to do a ebike tour along the Appian Way and a Foodie tour in Trastevere …

    Can’t wait to visit Rome..

    • Thanks Jane! You will love Rome. Sounds like you have done your planning’s high is key. If you need any more ideas, check out my article on hidden gems in Rome.


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